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Instead of efficiently storing incoming calories as fat, treated adipocytes become more metabolically active, breaking down stored triglycerides and releasing them for energy use

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Abstract The tumor suppressor p53 is a well-known cellular guardian of genomic integrity that blocks cell cycle progression or induces apoptosis upon exposure to cellular stresses

In addition, more clinical trials are required to validate the clinical utility of ferroptosis biomarkers such as MDA and GSH in early diagnosis and treatment decisions for CKD-related retinal lesions, improving the clinical translational potential of these findings