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doi: 10.1093/jn/131.9.2535S 26 NewsholmeP

Oxidative stress and inflammation: essential partners in alcoholic liver disease

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For instance, a landmark study on a human gut-liver-kidney on chip demonstrated the accurate replication of human-specific pharmacokinetics of cisplatin, predicting its dose-dependent nephrotoxicity which is a human-relevant outcome that can be poorly predicted by rodent models (211)