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When using RNA-seq technology based on techniques to observe the signal cascade reactions related to RGC death in retinal IR injury, it was found that the level of the Steap3 gene responsible for encoding the production of Fe 2+ and Fe 3+ was more than twice as high as that in the normal group

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et al., 2019) intraperitoneally into a rat model of SCI and found that the Xc-GSH-GPX4 axis was upregulated to inhibit Ferroptosis, thereby improving the functional recovery of SCI in rats