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melanogaster annotation from FlyBase (R6.35)

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This not only contributes to systemic inflammation but also impairs immune surveillance and responsiveness

Of note, ROS accumulation underlies RA, and the accumulated ROS has different effects over different cell types

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Mechanistically, several ADCs have been shown to induce ICD, characterized by the release of DAMPs, which promote dendritic cell activation, antigen cross-presentation, and subsequent priming of tumor-specific T cells [117]