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To demonstrate the finding of a previously unknown transsulfuration reaction distinct from the known ligation reaction, we first examined the isotopologue patterns of key metabolite substrates such as glutamate, glycine, serine, and cysteine in 293T cells labeled by a mixture of isotopic tracers ([U- 13 C]-glutamine, [U- 13 C]-glucose, and [U- 13 C]-acetate) (Fig

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Sulfhydration can modulate several physiological processes including responses to inflammatory stimuli, oxidative stress, neuronal signalling pathways and vasodilatation (Mustafa et al ., 2011

H.GinnanR.et al (2006)

Smeriglio et al., 2016)

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