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Overview of the mechanisms of oxidative stress: influence in inflammation of the airway illnesses

Melatonin induces drought tolerance by modulating lipoxygenase expression, redox homeostasis and photosynthetic efficiency in Arachis hypogaea L

Wazana A, Bresnahan M, Kline J: The autism epidemic: fact or artifact

Our recent proteomic study on a large collection of human liver microsomes (HLM) from donors with various degrees of alcohol exposure, besides confirming alcohol-induced expression of CYP2E1, also revealed upregulation of NADPH-cytochrome P450 reductase (CPR), CYP2B6, and CYP2J2, as well as downregulation of CYP1A2, CYP2C8, CYP2C9, CYP4A11, and cytochrome b5 [11]

thus, targeting PHGDH or SHMT to block DNA synthesis and epigenetic regulation represents a rational therapeutic strategy

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