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The documented preclinical effect on PC12 cells (pheochromocytoma) shows a reduction in calcium-dependent catecholamine release

Similarly, cancer cells growing under acidic conditions that simulate the tumor microenvironment accumulate lipid droplets

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Conclusion: These results showed that DWI+ and Gd+ lesions correlated with poorer clinical and functional outcomes at discharge in PRES patients, suggesting their potential in PRES prognosis