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The targeting mechanism of ENZ loaded FA-SNCD@SBA-15 (FA-SNCD@SBA-15/ENZ) is based on the specific interaction between the folate receptors on cancer cells and the folic acid ligand on the surface of the nanohybrid material

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A plausible explanation of this apparent dichotomy is that p53 promotes cell survival by preventing excessive increases in ROS under moderate oxidative stress, whereas when the oxygen species increase over a threshold level, it switches to becoming a ROS inducer, triggering cell death