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Genome-wide association studies of posttraumatic stress disorder in 2 cohorts of US army soldiers

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CTAR1 directly recruits the TNF receptor-associated factor (TRAF) family members TRAF1, 2, and 3 via its TRAF-binding consensus motif P 204 xQxT to induce noncanonical and atypical NF-B signalling, phosphoinositide 3-kinase (PI3K), and the mitogen-activated protein kinase (MAPK) pathways ERK and p38 (Fig

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The intestinal barrier is primarily maintained by tight junctions (TJs) between epithelial cells, which regulate intestinal permeability and prevent the invasion of pathogens and harmful substances into the submucosal layer