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2.1.4 Regulation of tumor cell redox homeostasis Gln regulates the redox status of cancer cells by influencing the production of mitochondrial ROS

Many thanks also to Sarahjane, Victoria, and the rest of the team for their excellent support and assistance with my queries

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Acute insults often cause multi-level damage including structural damage, metabolic stress and impairment of molecular homoeostasis, which trigger widespread homoeostatic failure

Glutamine, which is a nonessential amino acid (NEAA) due to the endogenous glutamine biosynthesis pathway, is currently considered essential in cancer cells because transformed cells consume glutamine at a rate exceeding that of glutamine biosynthesis 5