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Here's what studies have consistently shown: Wrinkle Reduction and Skin Tightening Multiple double-blind clinical trials have demonstrated that GHK-Cu reduces the depth of fine lines and wrinkles, with improvements in the 3050% range after 12 weeks of consistent topical application in higher concentrations

In rodent, intraperitoneal administration of chemotherapy drugs is often used

(Treasure Island, Florida: StatPearls Publishing)

What the evidence does not support Large-scale human clinical trials confirming safety and efficacy have not been published

PMID: 38797248 9 Vitamin B12 Deficiency: Recognition and Management

14 (4), e1007022