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Conversely, glucose deprivation suppresses SCAP (SREBP cleavage-activating protein) N-glycosylation, blocking SREBP activation, suggesting synergistic regulation of lipogenesis by glucose and ammonium (80)

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At the end of the slaughtering line, 20 min post mortem, livers were harvested and weighed

No differences were statistically different with other genotypes or other SFN metabolites

During tumor immunotherapy, IFN- released by activated CD8 + T cells also upregulates the expression of ACSL4 in tumor cells through the STAT1-IRF1 signaling pathway [111]

Cytotoxicity assays, including MTT and SRB, showed significantly reduced toxicity for the PEGylated nanoparticle formulation compared to free tolcapone (cell viability exceeded 85% at 10, 25, and 50 M of the formula after 24 and 48 h of treatment)