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It belongs to the CD33-related Siglec family which contains immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in its cytoplasmic tail and recognize sialic acids on host cells as self-associated molecular patterns (SAMPs) to dampen innate immune responses (177, 178)

Iio A, Ohguchi K, Maruyama H, Tazawa S, Araki Y, Ichihara K, Nozawa Y, Ito M (2012) Ethanolic extracts of Brazilian red propolis increase ABCA1 expression and promote cholesterol efflux from THP-1 macrophages

When the size of tumor reached 100 mm 3 , the mice were intravenous injected with PBS, Ru(II)-OH, NP2, and NP4 at the dose of 2 mg Ru/kg

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Immune checkpoint therapy modeling of PD-1/PD-L1 blockades reveals subtle difference in their response dynamics and potential synergy in combination

Further studies will be required to make full use of the Grx1-roGFP2-reporter EHM model, which will include investigations of the consequences of specific pharmacological (e.g., simulated neurohumoral overstimulation), biophysical (e.g., controlled electromechanical stimulation), or disease (e.g., hypoxia or ischemia/reoxygenation) stimuli for the ROS-mediated control of heart muscle function