glutathione synthesis in body Figure 2 from Glutathione Synthase | List of

J Nat Prod 73(4):623627 Li YJ, Xuan HZ, Shou QY, Zhan ZG, Lu X, Hu FL (2012) Therapeutic effects of propolis essential oil on anxiety of restraint-stressed mice

It is important to note that curcumin exhibits a biphasic dose-response relationship: lower doses activate protective pathwaysincluding increased total glutathione (GSx) and GST activitywhile higher doses deplete GSH, reduce related metabolites (e.g., taurine, homocysteine), and may induce pro-oxidant effects or cellular toxicity (Scharstuhl et al., 2009)

In conclusion, effective treatment is dependent on proper diagnosis

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After cooling to room temperature, trypsin (Promega, Madison, WI, USA, #V5280) was added and digested for 18 h at 37 C

Luyckx et al., 2021)