mk571 mrp1 glutathione efflux Genomic discovery and functional validation of as a novel fetal hemoglobin modulator and potential therapeutic target in sickle cell disease Nitrogen monoxide (NO)-mediated iron release

Nitrogen monoxide (NO) mediated iron release from cells is linked to NO induced glutathione efflux via multidrug resistance associated protein 1 PNAS Glutathione S transferase and MRP1 form an integrated system involved in the storage and transport of dinitrosyldithiolato iron complexes in cells ScienceDirect Protection against Oxidative Stress in Beta Thalassemia Hemoglobin E Erythrocytes by Inhibitors of Glutathione Efflux Transporters PLOS One The gut efflux pump MRP 1 exports oxidized glutathione as a danger signal that stimulates behavioral immunity and aversive learning Communications Biology MRP1 Dependent Extracellular Release of Glutathione Induces Cardiomyocyte Ferroptosis After Ischemia Reperfusion Circulation Research The efflux pump ABCC1 MRP1 constitutively restricts PROTAC sensitivity in cancer cells: Cell Chemical Biology

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