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The role of IDO activity in cataract progression: correlation to age and cataract severity

Because of the missing detectability, it remained unclear, if the level was the same or below the baseline, as observed in our study

In the medulla, an elevated UA concentration results in the deposition of urate precipitates and the activation of the Nod-like receptor protein 3 (NLRP3) inflammasome

In summary, our results suggest that -LA could attenuate pressure overload induced cardiac injury in an ALDH2 dependent manner, clinical studies are warranted to verify if -LA could be a potential useful therapeutic option to treat heart failure patients with pressure overload and with WT ALDH2

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