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Moreover, providing recombinant STAT3-activated cytokines that directly target hepatocytes, specifically IL-11 and IL-22, may be another novel pro-regenerative therapeutic option for patients with difficult-to-treat APAP-induced ALF [218]

With the development of time and technology, immunotherapeutic approaches for various leukemias have shown great promise, such as CD33 or CLL-1-specific chimeric antigen receptor (CAR)-T cell therapy[2, 3] and immune checkpoint inhibitor therapies such as TIM3, CD47, and anti-CD70 [4,5,6]

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Maolood N, Meister B (2009) Protein components of the bloodbrain barrier (BBB) in the brainstem area postremanucleus tractus solitarius region

In addition, the relative contribution of different ATP consuming reactions will strongly depend on the physiological situation, the activation state and the environment of an astrocyte, consistent with the reported heterogeneity of astrocytes [107, 114, 123, 124]

Identification of candidate long non-coding RNAs in response to myocardial infarction