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Proc Natl Acad Sci USA 102 , 1349613501 (2005)

This is clearly demonstrated by experiments in which the administration of the neurotoxin MPTP, which blocks Complex I of the mitochondrial electron transport chain, induces characteristic features of PD in mice [56, 57]

Inhibition of glutaminolysis by Gln depletion, by chemical inhibition of the critical regulators of Gln metabolism such as GLS and MYC, or genetic knockdown of these genes and Gln transporters resulted in the inhibition of the essential CSC-driving signaling mechanisms (e.g., WNT/-catenin

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Med Gas Res 6:7984 Huang P, Chen S, Wang Y, Liu J, Yao Q, Huang Y, Li H, Zhu M, Wang S, Li L, Tang C, Tao Y, Yang G, Du J, Jin H (2015) Down-regulated CBS/H 2 S pathway is involved in high-salt-induced hypertension in Dahl rats