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Description

Br J Cancer 111:10211046

Therefore, rigorous validation using human-derived organoids or patient-derived xenograft models is essential to ensure preclinical findings translate effectively to clinical contexts

Policymakers are now proposing to expand this approach across the entire DoD through a Strategic Breakthrough Funding program, with awards potentially reaching $30 million

In addition, knockout of Kir4.1 in rodent models has been reported to cause severe neurological deficits, including sensorineural deafness, ataxia, epileptiform activities, and early postnatal death (Nwaobi et al., 2016)