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Consistent with these findings, Gene Set Enrichment Analysis (GSEA) revealed enrichment of the SenMayo 30 and ferroptosis pathways in aged oocytes, indicating their transcriptional activation during oocyte aging, which were significantly attenuated by uridine supplementation, thereby reducing senescence-associated transcriptional features (Fig

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73 Some animal studies have shown that compared to the brains of animals not exposed to OPs, those of animals subchronically exposed to OPs for 25 days show phenotypic alterations in astrocytes, which are characterized by shortening, hypertrophy, and amoeboid morphology of cytoplasmic processes and detectable astrocyte hyperreactivity

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