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Table 2: Cytochrome P450 CYP1A2 Enzyme Substrates, Inhibitors and Inducers Pharmacogenetics-based Drug Dosing Guidelines in Psychiatry Personalized medicine requires development of resources for clinicians and pharmacogenetic dosing guidelines for medications as 25-50% of individuals do not respond normally to drug treatment and dosage 31

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In contrast to oncogene addiction, the inappropriate activation of c-MET resulting in oncogene expedience is the consequence rather than the cause of the transformed phenotype

NKT cell functionality is also modulated by GM: Bacteroides-derived lipid antigens regulate their activation state (Wieland Brown et al., 2013