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Similarly, in our cohort of liver specimens from patients with histologically confirmed end-stage MASH, among all the regulators of glyoxylate metabolism or oxalate formation, only AGXT was significantly suppressed as compared to healthy donors

Figure 2 4

however, the reported bioavailability values range from 10 to 98% 192,199,211

Potential therapeutic effects of exosomes packed with a miR-21-sponge construct in a rat model of glioblastoma