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If each physician deemed it necessary to prescribe a reduced dose of chemotherapy according to clinical manifestations such as age, ECOG-PS, and modestly impaired organ function, it was acceptable for patients to be administered reduced doses even from the first cycle

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Faubion SS, Sood R, Thielen JM, Shuster LT

the invention provides an embodiment which provides a sustained concentration of copper peptide in vivo of 12 + 2 meg/ml over 24 hrs from the time of administration

Historically, research focused on identifying AD drug targets and interventions have experienced significant failures with a 1% success rate (8)

Treatment Duration and Cycling Treatment duration and cycling follows patterns without evidentiary basis: active phase of 6-12 weeks continuous use followed by 4-8 week breaks