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Pharm Res 40 , 16411656 (2023)

Under these conditions, targeted LNPs must traverse the bloodstream and overcome organ-specific barriers en route to non-liver tissues (Figure 3, and (Mitchell et al., 2021

They also found that the mitochondria of rats pretreated with tocotrienol maintained the mitochondrial membrane potential without increase swelling commonly seen in cell death [52]

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Compared with contact lenses containing epalrestat or free drug solution, niosomes could encapsulate more drug (encapsulation efficiency 99.76%), increase the apparent solubility, protect the drug from premature degradation, and promote drug delivery to the intraocular tissues (75% drug release within 20 days)

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