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Fbxw7, is highly mutated in human cancers, and exhibits both truncating mutations throughout its gene body, as well as hotspot point mutations in its substrate binding motif

Have Digestive Disorders: Conditions such as Crohns disease or coeliac disease can impair the absorption of B12 from food

Biochemical, functional and pharmacological characterization of AT-56, an orally active and selective inhibitor of lipocalin-type prostaglandin d synthase J

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Feron VJ, Til HP, Vrijer F, Woutersen RA, Cassee FR, & van Bladeren PJ (1991) Aldehydes: occurrence, carcinogenic potential, mechanism of action and risk assessment

Additionally to the glycine biosensor, we have also designed and built constructs constitutively expressing the GcvA transcription factor, GcvR transcription factor and pepD using the Bba_J23100 promoter found on the iGEM registry of Basic Biological Parts