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Among children, approximately 12.5% globally are affected, with prevalence rising to 2145% in low- and middle-income countries

One potential peak week strategy would be to limit caffeine early in the peak week process (especially in chronic users, to restore sensitivity), employ it early in the day as a diuretic (e.g., on the day before competition) to limit adverse effects on sleep quality, and continue its use thereafter (e.g., upon rising the day of competition) to prevent withdrawal effects on both fluid homeostasis and/or mood and arousal [157]

Importance of indoor allergens in the induction of allergy and elicitation of allergic disease

As with any research compound, appropriate caution, informed consent, and medical supervision are essential

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