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mTOR signaling in brief and its role regulating cell metabolism mTOR is a serine (Ser)/threonine (Thr) protein kinase in the PI3K-related kinase (PIKK) family that forms the catalytic subunit of two distinct protein complexes, known as mTOR Complex 1 (mTORC1) and 2 (mTORC2) (Figure 1)

He had a positive evolution, with remitted knee arthritis after 12 weeks of MTX, thereby, prednisone was withdrawn in March 2023

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Renal inflammation reduces the expression of SLC7A11, a cysteine transporter, and impairs the glutathione synthesis pathway, resulting in low expression of glutathione peroxidase 4 (a ferroptosis inhibitor)

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