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Hazens team was the first to demonstrate that the metabolite TMAO is produced when gut bacteria digest choline, lechithin and carnitine, nutrients that are abundant in animal products such as red meat and liver

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This difference has been verified in the in vivo experiment (Fig

For this reason, these proteins represent potential targets for anti-cancer therapy and should be added to the existing list, including sugar and amino acid transporters, which are already considered druggable targets

In this context, the compounds FMC and IMC, identified by Roberts et al

Chapter 5 - repurposing nonantibiotic drugs as antibacterials, in Drug discovery targeting drug-resistant bacteria