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the stability of the protein is also given in mannitol-free preparations in the same way, but the solutions are then less well tolerated due to their lack of isotonicity

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It can be measured in urine and serum, and its levels correlate with the extent of tubular damage [109]

Under the favor of combination of the structure-based design and combinatorial chemistry, the efforts to synthesis a convenient structure are minimized [9]

L-arginine converts to citrulline and nitric oxide through NOS activity, while citrulline converts back to arginine through the kidney-based recycling pathway