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That turns a molecule designed for pulsatile behavior (in and out over a few hours) into something circulating at potentially 1,000 times normal elevation for nearly a week

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The number of immune-reactive cells was determined by counting positively stained cells on photomicrographs obtained from three random high-power microscopic fields (400 magnification) under a Leica DM2000 optical microscope, using a Leica DFC320 digital camera (Leica, Rijswijk, the Netherlands)

Patients who are on drugs that suppress the immune system are more susceptible to infection than healthy individuals

10.1136/gut.52.5.694 123 YangY.ChenL