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in preclinical models it activates the VEGFR2-Akt-eNOS signaling axis to promote angiogenesis and tissue vascularization ( It also engages ERK1/2 and FAK-paxillin pathways that regulate endothelial cell migration and fibroblast activity, and upregulates heat shock proteins (HSP70/90) for cytoprotective effects in gastrointestinal tissue models ( Research across multiple rodent injury models has characterized its activity in tendon, muscle, nerve, and GI tissue contexts

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S2CID 118726162

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Los estudios sobre las posibles aplicaciones de Ipamorelin explotaron a partir de finales de la dcada de 1990, y han abarcado desde condiciones clnicas muy especficas que necesitan opciones de tratamiento hasta la optimizacin de la salud en general