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Description

The intake level of dietary Met could affect the lipid and bile acid metabolism in the liver in mice, and Met-restricted diet could restore the normal bile acid pool in the liver (82)

Furthermore, DCI can occur in the absence of vasospasm and may affect brain regions distant from sites of vasospasm (23)

Embedded experimental medicine approach Incorporation of multiple readouts of a biological mechanism related to the therapeutic approach being tested within a clinical trial in order to understand the impact of the therapeutic agent on disease processes