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155 Ototoxic Drugs Some drugs have the potential to cause hearing loss or tinnitus because they are ototoxic (ie, toxic to the ear)

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Repeat several times, ideally every 2 hours if possible

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The authors concluded that co-administration of T3 and DHA enhances the capacity of liver for the resolution of inflammation by increasing RVD1 and RVD2 availability, so such co-administration constitutes an important hepatoprotective protocol for clinical purposes (118)

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Impairment of this process leads to conversion of H2O2 to hydroxyl free radicals, which causes cellular injuries in neuronal cells, which presents as delirium.[27] Predisposing Factors to Thiamine Deficiency Thiamine deficiency can result from conditions that restrict eating, such as orofacial cancers, or limit adequate vitamin absorption, such as gastric bypass surgery,[28] gastric and colon cancer, hyperemesis gravidarum, or starvation by choice or associated with sepsis, surgical complications, and coma.[27,29,30] By far the most common cause of thiamine deficiency throughout the world is alcoholism,[31] as described in landmark studies of alcoholic Wernicke-Korsakoff syndrome (WKS).[32,33] Individuals with alcoholism are at special risk for thiamine deficiency because of poor diet associated with their lifestyle and because chronic alcoholism compromises thiamine absorption from the gastrointestinal tract, impairs thiamine storage, and may reduce thiamine phosphorylation essential for cellular function.[31,3437] Table 2 outlines the predisposing factors for thiamine deficiency

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Changing the macrophage polarization in hepatic tissue toward M2 macrophages may exert protective effects against NAFLD progression and liver fibrosis

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10.1155/2021/9800794 540 ZhangH

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