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Under these circumstances a thiyl radical is formed that will initiate and propagate an oxygen-dependent chain reaction, involving peroxyl radical formation that will lead to further consumption of intracellular GSH (Quijano et al., 1997)

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More DPCs (proliferation) that live longer (anti-apoptosis) generating stronger growth signals, combined with a reduced stop-growing signal (TGF-beta-1 reduction), creates conditions more favorable to sustained follicle activity

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