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This helped to show that NNMT is a key target in metabolic research. Neelakantan and colleagues then expanded research involving small-molecule NNMT inhibitors

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Reconstitute with sterile bacteriostatic water or appropriate laboratory buffer Add solvent slowly along the vial wall to minimize foaming Gently swirl until the peptide is dissolved Store reconstituted solutions at 3646 F (28 C) Prepare aliquots where appropriate to reduce freezethaw cycles Careful reconstitution supports peptide stability and preserves functional integrity in experimental systems