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The functions of taurine include the improvement of mitochondria-related diseases such as mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes and aging-related diseases 35

Generally, nucleophilic sulfur atoms are oxidized preferentially by flavin monooxygenase, whereas nonnucleophilic sulfur atoms are oxidized preferentially by CYP450 (Ripp et al

Pepin ME, Konrad PJM, Nazir S, Bazgir F, Maack C, Nickel A, Gorman JM, Hohl M, Schreiter F, Dewenter M, de Britto Chaves Filho A, Schulze A, Karlstaedt A, Frey N, Seidman CE, Seidman JG, Backs J (2025) Mitochondrial NNT promotes diastolic dysfunction in cardiometabolic HFpEF

Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation

10.4161/gmic.21738 139 ValkoM.LeibfritzD.MoncolJ.CroninM

There is moderate emperical support, as there are studies available on these KER's but there is a lack of information on dose-response relationships in this AOP