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10.26508/lsa.201900547 102 SingletonM

Thus, while upstream stem cells do have the ability to differentiate into diverse cell types, in ALS, stem cells therapies are now intended to secrete neurotrophic factors, differentiate into astrocytes and microglia, or synapse with diseased motor neurons (Table 6) [271]

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The sample was then centrifuged at 12,298 x g using a Beckman Coulter optima XPN-90 Ultracentrifuge using Type 90 Ti rotor at 4 C

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