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In obesity, abnormal adipose metabolism transports large amounts of free fatty acids to the liver, increasing hepatic fat synthesis, decreasing fat breakdown, and ultimately causing hepatic steatosis

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The previously mentioned diseases are not only the main causes of disability, but also cause death in a short period, thus resulting in loss of the life years.[3] The notion, that obesity is primarily due to individual defects like pleasure-seeking behavior, no self-control or simply being over lazy, is still quite prevalent.[4] At present, the FDA has granted approval for long-term use of five medications against obesity in the United States