La recherche dmontre que les niveaux de glutathion dclinent de 20-40% avec l'ge, corrlant avec un stress oxydatif accru, une dtoxification altre et des maladies lies l'ge
As phase II enzymes, GSTs detoxify chemical compounds through catalyzing nucleophilic attack by the thiol group in reduced glutathione (GSH) on a wide range of electrophilic substrates [37, 40, 41]
doi: 10.1080/10408699891274273
The upregulated CD38 was also observed during the aging process, by secreted cytokines IL-6, interferons and soluble factors from senescent cells as part of so-called senescence-associated secretory phenotype (SASP) 21,27,36,47,48,49,50
Total Cholesterol (TC) 0.5ml of working reagent was added to a set of clean labeled test tubes and two of the test tubes were labeled standard 1 and 2 while another was labeled blank.0.1ml of homogenate was added to the approximately labeled test tube .mixed and incubated for 30 minutes at 37, the absorbance of the sample and standard were read against the reagent blank at the wavelength of 546nm
The short, medium and long fatty acid chains are oxidized in mitochondria whereas very long chain fatty acids are degraded by peroxisomes 67