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Muscle tissues were collected from rats and mice after euthanasia with an overdose of isoflurane in an induction chamber

Figure 4 4.1 Anti-oncogenic/oncostatic impact of melatonin on various cancer cells The concentration of melatonin in cerebrospinal fluid (CSF) and blood reaches its peak between 2:00 a.m

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The strategies to collect cuproptosis inducers originate from raising the intracellular Cu content and the intensity of mitochondrial respiration and TCA cycle, while the strategies to collect cuproptosis inhibitors originate from reducing intracellular Cu content, the intensity of mitochondrial respiration, TCA cycle, oxidative stress and UPS inhibition

This means the enzyme preparation likely still contains other proteins and compounds, which could influence the observed activity and characteristics

Oncogene 37 (4), 478488