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50 The microbiota plays a crucial role in various biological functions of the host, including the development of the immune system, protection from harmful microorganisms, food breakdown during digestion, and production of micronutrients and bioactive compounds

32 SeberA.ShuX

Acyl-CoA thioesters possess an electrophilic carbonyl-carbon and are able to undergo non-enzyme catalyzed transacylation reactions with biological nucleophiles leading to covalent binding to protein and drug-protein adduct formation

Oxymatrine attenuates CCl4-induced hepatic fibrosis via modulation of TLR4-dependent inflammatory and TGF-beta1 signaling pathways

5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor studied for its effects on NAD+ metabolism, cellular energy regulation, and adipose tissue models in preclinical research

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