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-Viniferin has been shown to activate AMPK in skeletal muscle and liver tissues, leading to promoting glucose uptake, fatty acid oxidation, and inhibiting hepatic gluconeogenesis (Hung et al

Pace E, Di Vincenzo S, Ferraro M, Siena L, Chiappara G, Dino P, Vitulo P, Bertani A, Saibene F, Lanata L, Gjomarkaj M

The buildup of reactive oxygen species (ROS) can result in damage to mitochondrial DNA, proteins, and lipids, as found by Radak et al

ncRNA networks serve a pivotal role in ARC pathogenesis by modulating gene expression, oxidative stress responses and pathological processes in LECs, indicating potential targets for early diagnosis and therapeutic intervention (134,200)

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