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According to clinical research parenteral administration (intramuscular or intravenous) is preferred over other drug administration routes in case of emergency situations as it provides first-pass metabolism avoidance, reliable therapeutic concentrations and better bioavailability of dosage (2) It can also be used in situations when oral route is not feasible

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For this, both utilization of substrate (MG) and generation of product (D-lactate) were measured in the same reaction mixture and a reverse correlation has been observed between them (Fig

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Such minor stress, which, for example, can be induced by pharmaceutical agents, can boost mitochondrial turnover and activate defensive mechanisms (Haigis and Yankner, 2010)

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Adjusting pH to a neutral range, where possible, can slow this decline, especially for sensitive products

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studies have shown that glutathione can be taken orally or intravenously

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For example, brain cells begin dying after just one minute of oxygen deprivation, and neurons suffer serious damage after just three minutes

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