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In humans, OCT1 is mainly expressed in the sinusoid membrane of hepatocytes, whereas in rodents, OCT1 is strongly expressed in the basolateral membrane of renal proximal tubule cells

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Discontinued Drugs Generally, for single source drugs and multiple source drugs for which negative or zero manufacturer's ASP data is reported for all NDCs and for which all relevant applications (for example, new drug applications (NDAs), biologics license applications (BLAs), or abbreviated new drug applications (ANDAs)) have a marketing status of discontinued on the FDA website, [300 301] we proposed that the drug be priced by MACs consistent with section 20.1.3 in Chapter 17 of the Medicare Claims Processing Manual for developing payment limits for covered drugs when CMS does not supply the payment allowance limit on the ASP drug pricing file

294 , L1127L1136 (2008)

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