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Optic Nerve Atrophy: Administering cyanocobalamin to patients with Leber's disease or hereditary optic nerve atrophy should be done cautiously, as it may worsen the condition

What's the best way to overcome elevated homocysteine levels and B12 deficiency is to maximize your methylation by changing certain lifestyle choices which include smoking cessation, getting enough exercise, eating a healthy, balanced diet, and taking vitamin B12 injections

Research shows that around 50 percent to 60 percent of ingested vitamin B12 is usually absorbed when enough intrinsic factor is present in relation to B12, but absorption decreases drastically when this ratio changes

However, bioavailability is variable (so levels should be monitored when transitioning from IV to PO)

However, as you get older or if you drink heavily, it's a good idea to keep an eye out for symptoms of low B12

Key Takeaways Research-grade 5-amino-1mq dosage protocols typically employ 50100mg daily, administered subcutaneously or orally, with subcutaneous routes offering 7085% bioavailability versus 4050% oral