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Ferroptosis is a form of cell death driven by the accumulation of iron-dependent lipid peroxides, and it differs from traditional forms of cell death such as apoptosis and necrosis ( In lung cancer, the expression profiles of GPX4 (glutathione peroxidase 4) and SLC7A11 (solute carrier family 7 member 11) are closely associated with patient prognosis

Macrophages reside in almost all of the lymphoid and non-lymphoid tissues [8]

In the reaction (equation 2), X is the herbicide and Z is the leaving group

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For instance, baicalin has been reported to enhance cell resistance to ferroptosis by inhibiting erastin-induced GPX4 degradation and suppressing ACSL4 expression (219)