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Other inhibitors have faced challenges, such as poor specificity or high toxicity, which prevent their progression to clinical trials

Jedrychowski W: Biological meaning of the prospective epidemiological study on chronic obstructive lung disease and aging

After cloning in pGEMT (Promega) the resulting plasmids (Supplementary Table S1) were opened at the unique Sma I site where we cloned the Km r cassette (a Hin cII fragment of the commercial pUC4K plasmid) in the same orientation as the coding sequence it replaced

Moison, C

Angiotensin-converting enzyme inhibitors (ACEis) or angiotensin-receptor blockers (ARBs), commonly used to treat heart failure, may cause zinc deficiency [112]