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Furthermore, it was determined that 27 thiadiazole derivatives had been synthesised, with 4d exhibiting a greater degree of GLS1 inhibitory activity than the known GLS1 inhibitors, DON and A

J Neurol 259:24342439 Bonnefont-Rousselot D, Lacomblez L, Jaudon MC, Lepage S, Salachas F, Bensimon G et al (2000) Blood oxidative stress in amyotrophic lateral sclerosis

At the time, the FDA estimated it would issue final regulations before the end of 1978

Anderson JR, Khou S, Nawarskas JJ

After 24 h of treatment, the injury of HK-2 cells was even deepened as showed in the cells incubated with the highest concentrations of the tested compounds (Fig

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