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Jassim H, Seligman JT, Frelich M, et al

10.1002/adhm.202401103 52 GruberH

Supplementary material The Supplementary Material for this article can be found online at: Abbreviations DILI, drug-induced liver injury

DISCUSSION In this study, we show that, mirroring the widespread yet heterogenous down-regulation of the UCEs in patients with HCC, a collection of HCC mouse models displayed divergent UCE expression levels, with substantial repression in several carcinogenic and oncogenic models including those driven by -catenin but not by silencing the tumor suppressor Axin1 (Fig