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The net effect is decreased mucociliary clearance, which is undesirable in patients with chronic lung disease

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The second limitation was the relatively low number of stress oxidative factors evaluated in this study

Certain of these previous reports were able to pinpoint the specific cysteine residues which were modified in the GSTs, namely Cys50 in rat and human MGST1 (Shin et al., The analysis of proteins and their modifications benefits from continual advancements in liquid chromatography-tandem mass spectrometry (LC-MS/MS), a broadly used tool for proteomic investigations (Aebersold and Mann, In this work, several analytical approaches (Figure 2) were investigated combining different techniques for sample preparation and LC-MS/MS analysis to identify APAP-related covalent binding to purified human GSTs (overview in Table 1, note: Met1 is considered here as the first amino acid in protein sequences throughout the whole manuscript)

pneumoniae strains, and found that thymol, carvacrol and geraniol exhibited the most promising antibacterial and antibiofilm activity against uropathogenic New Delhi Metallo-beta-Lactamase-1 (NDM-1) producing K